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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39592d845614d2233aa43c6df5e10e7b483683327cb7497ca44e5b6c1a2e687c' 
  AND token = 'i8c4UWsIvnX01i3SyzzZTjDeE7ypaVMn/xCVo0xWU7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}