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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a64bae975af2009ea15b28350a8f35a45d05ff474b76c2a2e7a708b70e66e3c4' 
  AND token = 'US959MbW2Hdq+8SRaLpjy02zr0V0dGCgjnaojPNSwHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}