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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97b9975ced11753585127999ba6f6c930e9ea7bc5ccb65dc48f8e5e601f25507' 
  AND token = 'UEAcww7iY0xg0JUDGgEabPEemFBB+CHWZ8Uj2g1SSpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}