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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22ce6ba41e807674cdee5efc5a439574d80e5b224d5d1a84a08f39f09e78916' 
  AND token = 'MDa6/9CpJLgnJe1GXAkTULKpiZbrRmmA57tzxWii2jM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}