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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43af9fa789ac041e92fa0ef690d167579ca6ab3bdadd1cd8b2bf4006c805da05' 
  AND token = '1x2L4RbJfFGhkF9i5bY4/wE4aDRmLshmm4bLyYZbT58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}