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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68250651540b5c91f1ca44fcaca2f3b9370c3a42b3f30dc88b76c44900ae957f' 
  AND token = 'XbMlig2pqpw2JpbHuM++pnb6l7xZAgUn5gDMYWbE+R8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}