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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a135c59582d3d3fc59dfd2f74c8ad2f5f4484a90dcaad1eee52ce5c2ecaf43d' 
  AND token = 'k2r/YzZXqmp4edIphinrkTLI5wwiy4BzCZPnO6Vk4uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}