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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e385cee214341cd10ec7288f3d12124a9816f229d32d5a18c6a3743420f84b31' 
  AND token = 'M8pMf0MZIZ6O1EkNPcw0lA9nLSgEqEkvCD/Ps6CzcZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}