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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0184aa383baa154224e1f0307a0ad923bdd16927dcd12f8b719351e21c7841d' 
  AND token = 'rA78u+J+KyVyRtlyY0d/Wpc2OUGMY3YdNRutVRyjlHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}