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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b437428aa5074ee74645e1e5f381bac7f6e636b5083d75c8043eb66f9678306' 
  AND token = 'UaJMWvmaOOA5BLaCIsFLeMLst5KMglxjJt+vD645XSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}