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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac9fbc9c021f39b7bee516cf916cbdb0357730448ab18c450dc832061c0f9d71' 
  AND token = 'bYPIZaRChS1KDXGrzxow7UgEiUGZ/I27ojmb3t90Is8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}