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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0745244b8863ed71e2ce387609ca9e10d5f7d2b3896b7987ca38a7cccd4b4d24' 
  AND token = 'IzvvBz8qSsMtZJc8ESt+sIrR6oHS75ZRoPxhCFqDBek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}