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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f2791e5562f3795e4509cdde5c29c92bb6ffc28f9f885de4ab36da2352b157' 
  AND token = 'eN63C3LryD8lfyiwxpekddwo0uoGjUFm2dx4X/8IWFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}