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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd78434ce711988c7c5bf6316fe90c7d86ea465d1b4ea4cb49399081fc79298' 
  AND token = '7GJrc432UbGltafqE6M9j++8DnrVRIVY3lf/j8cNMRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}