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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e9d8b4d88e884312980a3edd6dd966f2d8f6319542ba9fb49715952d1347aa' 
  AND token = 'szbgrEdTpDXQ7qVAL9JiNtkPOcV+6p1qhaY42Kzo1ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}