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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a581de40988657e1f25e9ae21c16d9296a6f1e53295ec1731d5c65ff494c55aa' 
  AND token = 'N7Hvv5G0WUEU7t77hM7r0CzZbHBVBkF7/zBRyP2CyZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}