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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f78c35eade61ab3daf29b082c27a6275c6313430bd2c4811ec20623f6f683364' 
  AND token = 'c/VPk7e2sn/b7bSgRvhX90fIzzHHT1wQtiGNnKigE1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}