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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4a01aa0a38460b51cb3dd50a2cc2cd97a256b0dcf3fe78615f472227c0ef7b4' 
  AND token = 'ZAwMFuiUr6IvAZBWuyqHWUaVq391TNsXu7f6UmueCaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}