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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680f947e3181f3725f783652b342ebb66b3655d8d1cffdd5efb6f19b04e6c1f7' 
  AND token = 'VST/3ElJu4KL88yoOnXY73nEUnpY699tfeDYDL74RC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}