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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cefe15e750eacae751595469c82713d00ac8336ec8ffff05fdb281d637252b4b' 
  AND token = 'a7v+RKEGCDdF1yCT3rGqG5cW7NX6rr31Dhf+r/sxL/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}