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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b05f36f29d291dc96fab6d7f88c4d279b61cc1addd2e6bf79c324121abad843d' 
  AND token = 'Wxb81EhXjyUGHH/3FZIkSEUbVWgqHbUgeNbXyJUvRIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}