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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0800c9b3d625dffd1882fa6e3d1328a4505a70c1254d5f37f87e80e79aac6034' 
  AND token = 'hm+QwbVnFMwXAXAzU49HLBaNkkL19iBMYnxP1RRwZAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}