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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e59aeb4ccf9db39949de66282e223c95dbc9bbbcf387aa2779801de1061b62ca' 
  AND token = 'F0n3WqCDldcesU8csQT59Vqhkq3cif+FJTOvUJYoX1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}