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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4c1b6006340f75efede5c90f201acd140e033d188db1d69fd2b67a2e195ec2d' 
  AND token = 'pWeYF/3HLZOywx9bEaNFoUBhc3830Ei4xJSZg3ta4F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}