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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '325aaf46c2cd7e4416d035a552a7a5651ce9e90180949c8b073681e3b19c0a49' 
  AND token = 'd8y2oswEWseugFsdCMZdRH+3emFBPIFENi01zmEoHQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}