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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d5e01d0bb01a4004e21b6d6ee9b98957415355ee1b5c7a2943302a3120d5cb8' 
  AND token = 'TQfYYgMqF0aIKCJBu6rwgL1B69Pa66QT8RPu7zY8WV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}