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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04e5e2f5b131af89ee40a45da28de4efb5869a165b62534c73125becb4c21feb' 
  AND token = '64I/NpB3viIWcnkU87FxgKDe5jPNZzjw0WIXAW9bTdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}