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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c618690781d0e167351259b64f9a99dc45ef199bb5a3428b614d1dcc11880d8' 
  AND token = 'CRlUIGMRnWbMnA138l30bFH3RPSeo9FpeeYK1cK82Yk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}