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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16c0200d49ce27059ac1d8171786af68a168f8c91e37cb2794ba8f33e0dcc67f' 
  AND token = 'ZoJckqgOrZAvYg5/CPAIYjk+yJMxdlpOZhTacWQb4E4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}