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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64343de178f383f31d4050f59bad6b3bd496e9af2e18d2ad24f123ac65872aba' 
  AND token = '5dw33df0K202RKgk5EGWXu7KGGQdfn7TqrnMl4QS6OI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}