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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5a2a74f15b95eb9ed372763c4018ba73fbf4aa6f384e4cf5a7fca096b8c7401' 
  AND token = 'hMcNc9lMWYgHJNkBTKpkJV1CfN6vOpCR8pO1CfH8EZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}