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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1f89931c8f4c341fc7a857cee3a8ea03fa971597b8a0dc0eee50454e2905615' 
  AND token = 'HTPmK6rqUz16CaQb2Ns3NiuI9ZfeM74ZvVzFOUX2vdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}