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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bc36a22ebb29c93884d3ecfa645bcf743d9e959e91b18e28a442c249a15b15c' 
  AND token = 'OFbFODta0Ldp/Eb87dWnONRCmn1LBjYJsfe8YpxTXuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}