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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e66945b1ca1ceb8351b7f776d15b159127d03978024e8da318339d21e67dae7' 
  AND token = 'NlJbYA+Ig/NBhOinxuPrZEYDt5ZEbncPcsrd7NY7d88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}