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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c7f5d10b743c23935cc9ce41a7c6867aa65fdc9f10b1de578bcbdc52f9c9b64' 
  AND token = 'pmxgzsCnO72ZHa+BI6GG5HHe5ix6cHqw1LHgFtUssMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}