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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a3b1406e02985385c0d0511195d4c0b76573137536ce85a526518084d84e93a' 
  AND token = 'SxpxAfvHuzn2PTRtH70qF2WlqwmCdmxjNFc2dZQFyIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}