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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa69fb73f57eafe0b57002728e44fb0764b02572ed17e48a89b203d31e88e38f' 
  AND token = 'otLtsxE0ltGPICEGvFRuSA38jpiAhHfPKdfhApGcefM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}