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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e013d5087d4c8d9f41cc7b08806f049439e376e1c00a86c156111b04b2e12ccb' 
  AND token = '5Zy6F+mT5eeN9/+CvA4dhnI0LfFw2fLc8sjOjRk6zVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}