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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a52aed72131f401d6c316ca9a1a7912b4ad0330e36c48d46f0e4e47955c9d1e' 
  AND token = 'NRoxaM/LbrMICeQ5IjNh0Z/9rYma5ZmoOPejUPK/M6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}