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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10408765a7e1d04a2c0d07c4120398ea5a00af02deb9e8dddfd60984c5137ff2' 
  AND token = 'oW42L/W+YKMDmHSBLuId8m4yvKQKjNQsD5kzQrtow18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}