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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1910997b9f017e1acaf3178960d0d8f1fd8c009c4486b1473beb1295b0024f3' 
  AND token = 'HQZ8n4+W/K/vmpwl6O+23746peRPSUabLgLyjxvMp3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}