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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b49e733f87e67ba0efa7dbebf710078f1d789240dc63d7f7c02f1406e3baf23a' 
  AND token = 'wdCFBw4CJztrnWiPCJLXzteVVs63ASiGk72PowCxxOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}