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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0d9dd7b240c759b5c826140e024e83bd9f0dca55279fb7edadb12720e327d4a' 
  AND token = '+rxiTvQP4iQ7GsJVFg3BtHgsV769WJXM9YY37zgS1gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}