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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48efa16a5d255393b71a8aaa51051f9cda1d01f3da9532d049c0e45e8040c1d1' 
  AND token = 'Rf79kpt092z3q1eCOU+ajVYstFbI+ogPh1tz8h0oq2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}