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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a9e18a5fba2e087645aa78796deb0442e4df0c3af4695ba1bfe1c7f91de39e8' 
  AND token = '8DJGmo0XMZh5NDNNQnchGhSAwEhqEOY25++kmBjHlZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}