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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff7a25632d45d6140d12c572b47201a6519fc50cc6d2bf747f92bfc59edef9c5' 
  AND token = 'SJO842LuNEYtG7ed2TaWq1XEzYF/nge/Ie7QbYWN6KU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}