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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3beb4b4ea03787ce7888627d548cd9e3dba0a553275422b2d9585bf82e1c635' 
  AND token = '48HI2oSvZVWRSnD0F8wxfdsE5weUWBvzdlV6soVkwCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}