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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9749cacea7cfb1edf4008133549515a12195273b7e2267514573f496d0f054f6' 
  AND token = 'mDZgNtOTO2Fyb2WgtZ9N01Ust/GvMYC6uKo90Tzx6JU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}