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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '651357d84f2384de3d335f79d933464ab4f8109381df94f0391a5316e5e63901' 
  AND token = 'L377R3xCofQB0eL3xnXOGtoscx1sG2mZk79UeeAwAFY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}