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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50e10757d2ab4a7d33b78c0b3c64b2298dbe36fb9c867770b18314739aeceee8' 
  AND token = 'SkbOT+m3k3s3BlQw8K+uY9UtInRyPuf+l1BLa+jQyoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}